Novel brain expression of ClC-1 chloride channels and enrichment of CLCN1 variants in epilepsy
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چکیده
منابع مشابه
Novel brain expression of ClC-1 chloride channels and enrichment of CLCN1 variants in epilepsy.
OBJECTIVE To explore the potential contribution of genetic variation in voltage-gated chloride channels to epilepsy, we analyzed CLCN family (CLCN1-7) gene variant profiles in individuals with complex idiopathic epilepsy syndromes and determined the expression of these channels in human and murine brain. METHODS We used parallel exomic sequencing of 237 ion channel subunit genes to screen ind...
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ژورنال
عنوان ژورنال: Neurology
سال: 2013
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0b013e31828868e7